对急性呼吸窘迫综合征诊断新标准( 柏林定义) 的解读和探讨_中国呼吸与危重监护杂志

作者：

解放军总医院南楼呼吸科( 北京 100853);

关键词：

急性呼吸窘迫综合征诊断

DOI：

10.7507/1671 -6205.20130001

视频：

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过去10 多年来, 急性呼吸窘迫综合征( ARDS) 的基础和临床研究取得了巨大进展, 也暴露了目前临床上正在应用的ARDS 诊断标准的重要缺陷。近年来已经有多组学者提出了重新制订ARDS 诊断标准的建议。为今后更好开展前瞻性多中心随机对照研究( RCT) , 也迫切需要一个诊断新标准来统一和规范病例的选择。

引用本文： 俞森洋. 对急性呼吸窘迫综合征诊断新标准( 柏林定义) 的解读和探讨. 中国呼吸与危重监护杂志, 2013, 12(1): 1-4. doi: 10.7507/1671 -6205.20130001 复制

1.	Pauwels RA,Buist AS,Ma P,et al;GOLD Scientific Committee. Global strategy for the diagnosis,management,and prevention of chronic obstructive pulmonary disease:National Heart,Lung,and Blood Institute and World Health Organization Global Initiative for Chronic Obstructive Lung Disease (GOLD):executive summary.Respir Care,2001,46:798-825.
2.	Fang X,Wang X,Bai C. COPD in China:the burden and importance of proper management. Chest,2011,139:920-929.
3.	曾雪峰,王晓霞,包勇,等. 成都市社区慢性阻塞性肺疾病流行病学调查.中国呼吸与危重监护杂志,2011,10:30-32.
4.	中华医学会呼吸病学分会慢性阻塞性肺疾病学组.慢性阻塞性肺疾病诊治指南(2007修订版).中华结核和呼吸杂志,2007,30:8-17.
5.	GOLD Science Committee. Global Initiative for Chronic Obstructive Lung Disease(updated 2013). http://www.goldcopd.org.
6.	Woodhead M,Blasi F,Ewig S,et al. Guidelines for the management of adult lower respiratory tract infections-summary.Clin Microbiol Infect,2011,Suppl 6:1-24.
7.	Blasi F,Ewig S,Torres A,et al. A review of guidelines for antibacterial use in acute exacerbations of chronic bronchitis.Pulm Pharmacol Ther,2006,19:361-369.
8.	Sethi S. Infectious etiology of acute exacerbations of chronic bronchitis.Chest,2000,117:380S-385S.
9.	Sapey E,Stockley RA. COPD exacerbations. 2:aetiology.Thorax,2006,61:250-258.
10.	Kherad O,Kaiser L,Bridevaux PO,et al. Upper-respiratory viral infection,biomarkers,and COPD exacerbations.Chest,2010,138:896-904.
11.	Daniels JM,Schoorl M,Snijders D,et al. Procalcitonin vs C-reactive protein as predictive markers of response to antibiotic therapy in acute exacerbations of COPD. Chest,2010,138:1108-1115.
12.	Miravitlles M,Kruesmann F,Haverstock D,et al. Sputum colour and bacteria in chronic bronchitis exacerbations:a pooled analysis.Eur Respir J,2012,39:1354-1360.
13.	慢性阻塞性肺疾病急性加重诊治专家组. 慢性阻塞性肺疾病急性加重诊治中国专家共识(草案).中国呼吸与危重监护杂志,2013,12:541-551.
14.	Mallia P,Footitt J,Sotero R,et al. Rhinovirus infection induces degradation of antimicrobial peptides and secondary bacterial infection in chronicobstructive pulmonary disease.Am J Respir Crit Care Med,2012,186:1117-1124.
15.	Rosell A,Monsó E,Soler N,et al .Microbiologic determinants of exacerbation in chronic obstructive pulmonary disease.Arch Intern Med,2005,165:891-897.
16.	Sethi S,Murphy TF. Infection in the pathogenesis and course of chronic obstructive pulmonary disease.N Engl J Med,2008,359:2355-2365.
17.	Sethi S,Evans N,Grant BJ,et al. New strains of bacteria and exacerbations of chronic obstructive pulmonary disease.N Engl J Med,2002,347:465-471.
18.	Chen JI,Slater LN,Kurdgelashvili G,et al. Outcomes of health care-associated pneumonia empirically treated with guideline-concordantregimens versus community-acquired pneumonia guideline-concordant regimens for patientsadmitted to acute care wards from home.Ann Pharmacother,2013,47:9-19.
19.	Martinez FJ,Han MK,Flaherty K,et al. Role of infection and antimicrobial therapy in acute exacerbations of chronic obstructivepulmonary disease.Expert Rev Anti Infect Ther,2006,4:101-124.
20.	Li XJ,Li Q,Si LY,et al. Bacteriological differences between COPD exacerbation and community-acquired pneumonia.Respir Care,2011,56:1818-1824.

1. Pauwels RA,Buist AS,Ma P,et al;GOLD Scientific Committee. Global strategy for the diagnosis,management,and prevention of chronic obstructive pulmonary disease:National Heart,Lung,and Blood Institute and World Health Organization Global Initiative for Chronic Obstructive Lung Disease (GOLD):executive summary.Respir Care,2001,46:798-825.
2. Fang X,Wang X,Bai C. COPD in China:the burden and importance of proper management. Chest,2011,139:920-929.
3. 曾雪峰,王晓霞,包勇,等. 成都市社区慢性阻塞性肺疾病流行病学调查.中国呼吸与危重监护杂志,2011,10:30-32.
4. 中华医学会呼吸病学分会慢性阻塞性肺疾病学组.慢性阻塞性肺疾病诊治指南(2007修订版).中华结核和呼吸杂志,2007,30:8-17.
5. GOLD Science Committee. Global Initiative for Chronic Obstructive Lung Disease(updated 2013). http://www.goldcopd.org.
6. Woodhead M,Blasi F,Ewig S,et al. Guidelines for the management of adult lower respiratory tract infections-summary.Clin Microbiol Infect,2011,Suppl 6:1-24.
7. Blasi F,Ewig S,Torres A,et al. A review of guidelines for antibacterial use in acute exacerbations of chronic bronchitis.Pulm Pharmacol Ther,2006,19:361-369.
8. Sethi S. Infectious etiology of acute exacerbations of chronic bronchitis.Chest,2000,117:380S-385S.
9. Sapey E,Stockley RA. COPD exacerbations. 2:aetiology.Thorax,2006,61:250-258.
10. Kherad O,Kaiser L,Bridevaux PO,et al. Upper-respiratory viral infection,biomarkers,and COPD exacerbations.Chest,2010,138:896-904.
11. Daniels JM,Schoorl M,Snijders D,et al. Procalcitonin vs C-reactive protein as predictive markers of response to antibiotic therapy in acute exacerbations of COPD. Chest,2010,138:1108-1115.
12. Miravitlles M,Kruesmann F,Haverstock D,et al. Sputum colour and bacteria in chronic bronchitis exacerbations:a pooled analysis.Eur Respir J,2012,39:1354-1360.
13. 慢性阻塞性肺疾病急性加重诊治专家组. 慢性阻塞性肺疾病急性加重诊治中国专家共识(草案).中国呼吸与危重监护杂志,2013,12:541-551.
14. Mallia P,Footitt J,Sotero R,et al. Rhinovirus infection induces degradation of antimicrobial peptides and secondary bacterial infection in chronicobstructive pulmonary disease.Am J Respir Crit Care Med,2012,186:1117-1124.
15. Rosell A,Monsó E,Soler N,et al .Microbiologic determinants of exacerbation in chronic obstructive pulmonary disease.Arch Intern Med,2005,165:891-897.
16. Sethi S,Murphy TF. Infection in the pathogenesis and course of chronic obstructive pulmonary disease.N Engl J Med,2008,359:2355-2365.
17. Sethi S,Evans N,Grant BJ,et al. New strains of bacteria and exacerbations of chronic obstructive pulmonary disease.N Engl J Med,2002,347:465-471.
18. Chen JI,Slater LN,Kurdgelashvili G,et al. Outcomes of health care-associated pneumonia empirically treated with guideline-concordantregimens versus community-acquired pneumonia guideline-concordant regimens for patientsadmitted to acute care wards from home.Ann Pharmacother,2013,47:9-19.
19. Martinez FJ,Han MK,Flaherty K,et al. Role of infection and antimicrobial therapy in acute exacerbations of chronic obstructivepulmonary disease.Expert Rev Anti Infect Ther,2006,4:101-124.
20. Li XJ,Li Q,Si LY,et al. Bacteriological differences between COPD exacerbation and community-acquired pneumonia.Respir Care,2011,56:1818-1824.

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